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SERUM game title screen with glowing green injector in sci-fi survival setting

Exploring Serum a New Benchmark in Survival Games Early Access Review

Posted on May 22, 2024June 21, 2025 By Ronny Fiksdahl

Inject or Perish: This Grim Sci-Fi Survival Puts You on a Two-Minute Timer

Reviewed on PC | Early Access

Thrown Into the Unknown

In SERUM, you’re not stranded on a sunny beach or dropped into a forest. You’re a scientist—and your first waking moment is inside a tunnel-like sewer, not even remotely safe. From the get-go, you’re forced to inject a substance called Serum every two minutes to survive. And if that’s not bad enough, your colleague’s ominous radio transmission confirms you’re very much alone—and in deep trouble.

SERUM

Release Date: Early Access (2024)

Genre: Survival, Exploration, Crafting

Developer/Publisher: Team Game Island / Toplitz Productions

Platforms: PC (Steam)

Mission Impossible?

Eventually, you stumble upon a base—your only reprieve from the Serum countdown. It’s here you learn to craft your own supply. The game’s loop is about managing time, making trips out into the wild, and coming back alive. You’ll be growing ingredients, recycling gear, crafting weapons, and expanding your equipment. While there’s no building system like in other survival games, the base serves a core survival function more than a creative one.

Crafting and Surviving

It took me about an hour to locate the spear recipe, and the same for the bow—which, by the way, has unlimited arrows. I spent a lot of time exploring, dying repeatedly, and learning slowly, and honestly, I wouldn’t have it any other way. Every death means starting again at your last-placed defibrillator, which adds a layer of strategy to exploration that I genuinely appreciated.

Our Gameplay Video:


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Gameplay Experience

Across my 10–15 hours of gameplay, I experienced frame rate dips—from 100 FPS down to 50 in certain areas. They weren’t game-breaking, but they were noticeable. A few places could potentially get you stuck, but nothing that ruined the experience. The ambient sound design deserves special mention: the eerie whispers and audio cues added real tension, often getting under my skin even when I didn’t consciously notice them.

Combat and Exploration

Your best weapons early on are the spear and bow, both great for keeping distance. Resource planning is crucial. Serum can be brewed with various ingredients, creating effects that extend duration, improve stamina, increase jump height, or let you break through blocked areas. Farming plants at your base for future brews reminded me of systems in Far Cry and Green Hell.

SERUM gameplay screenshot showing spear in toxic green forest – survival game scene

Blending Survival and Lore

SERUM excels at making you feel like time is always against you. You explore through dense fog, mutated wildlife, and increasingly toxic zones. You’ll uncover journals, environmental storytelling, and hints at past experiments gone wrong. The brewing mechanic is where things get fun: mix different resources to modify effects and side effects. All while managing health, stamina, and your supply of Serum.Official SERUM key art featuring combat traps

What’s Coming Next?

I haven’t delved deeply into the trapping or animal breeding systems, but the game hints at a deeper layer still to be explored. And on the horizon? A 4-player co-op mode, giving players a chance to survive together. Since SERUM is still in early access, I’m optimistic we’ll see even more game-changing additions soon—whether that’s new quests, biomes, animals, or DLC.

Final Verdict

SERUM isn’t just another survival game. It’s a genuinely unique take on the genre with tight pressure mechanics, clever crafting, and an unsettling world that constantly keeps you on edge. We’ve followed its development from early demo coverage to our exclusive interview with the developers at Game Island, and I have no doubt it’s heading toward something special. Fix Gaming Channel gives SERUM a solid 9/10.

Stay tuned for more survival spotlights and exclusive interviews right here on Fix Gaming Channel.


Written by Ronny Fiksdahl, Founder & Editor of Fix Gaming Channel.

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Indie, News, Reviews Tags:early access games, Indie Games, PC, PC Gaming, Serum, survival games

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